Novel optical CO2 sensor technology in long-term cell culture

In mammalian cell culture, the monitoring and controlling of CO₂ important to provide the cells with physiological environment. Deviations from the desired levels can affect cell growth, viability and product quality. CO₂ levels are usually measured offline and thus accurate CO₂ probe for constant online monitoring would be desirable.

In a collaboration within iConsensus WP4, a novel optical CO₂ probe was developed by PreSens and evaluated by an industry partner GSK in a stirred-tank bioreactor. Read the complete application report